Sorting out male and female sperm

A new sperm separation technique may one day allow prospective parents undergoing IVF to choose whether they have a boy or a girl before fertilisation takes place, researchers say. Scientists in Japan have reported a new method which allows them to separate mouse sperm carrying an X chromosome from those carrying a Y chromosome, meaning that sperm can be selected based on whether they will result in female XX or male XY offspring when used to fertilise an egg. The researchers say they made their discovery as part of a project to unpick and understand the differences between sperm carrying an X chromosome or a Y chromosome, noting that the former carries far more genes than the latter. The scientists say their work could also prove useful in agriculture. While there are already existing methods such as flow cytometry that can be used to sort sperm, these are based on the relative size of the X and the Y chromosomes and are expensive.
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21.08.2020
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Sperm Sorting

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Methods Of Gender Selection - Sperm Sorting - IVF with PGD

By Michael Le Page. You could start to do it in your bedroom. However, Fazeli thinks it may not be necessary to select the fastest or slowest swimmers before insemination or IVF to influence the sex of an embryo. Seidel agrees.
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Sperm sorting method could prevent girls being born, scientists warn

A new chemical treatment that can segregate male and female sperm could one day mean parents going through IVF could choose whether they have a boy or girl. Scientists discovered the sperm with the X chromosome which gives rise to females slowed down when when a certain chemical was added while sperm with the male Y chromosome sped up. In experiments with mice sperm, scientists found they could produce litters that were 90 per cent male, according to the study published in Plos Biology.
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Sperm sorting is a means of choosing what type of sperm cell is to fertilize the egg cell. Several conventional techniques of centrifugation or swim-up. Newly applied methods such as flow cytometry expand the possibilities of sperm sorting and new techniques of sperm sorting are being developed.
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